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Continuing Education Information

Physicians: Physicians' Education Resource is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

This activity is approved for AMA PRA Category 1 Credit

Physician Assistants: AAPA accepts category 1 credit from AOACCME, Prescribed credit from AAFP, and AMA Category 1 CME credit for the PRA from organizations accredited by the ACCME.

Targeted Therapy: Increasing Therapeutic Alternatives in Metastatic Breast Cancer

Fontainebleau Miami Beach Hotel
Miami, FL
March 5, 2009

Conference Overview

Oncology CME-Certified Symposium

Held in conjunction with the 26th Annual Miami Breast Cancer Conference

For today’s oncologists, the rapidly evolving area of targeted therapy for breast cancer leads to challenges in patient care and treatment decision making. For patients with ErbB2+ disease in the metastatic setting, disease progression following prior ErbB2-targeted therapy is common; several recent studies have addressed therapeutic options, such as utilization of small-molecule tyrosine kinase inhibitors with chemotherapy, combination regimens coupling 2 ErbB-targeted agents, or inhibitors of interrelated pathways, for this patient population. Another area of debate is treatment strategy selection for the frontline treatment of patients with ERB2+ metastatic breast cancer. Traditionally, treatment options included an ErbB2-targeted agent with or without chemotherapy but recent studies have suggested that, for some patients, combining targeted therapy with a hormonal agent might be effective, while ongoing trials are examining the potential efficacy of all-biologic regimens combining ErbB2-directed and antiangiogenic agents. The Targeted Therapy: Increasing Therapeutic Alternatives in Metastatic Breast Cancer symposium will review and discuss the latest information on biologic therapies for ErbB2+ metastatic breast cancer. A presentation of relevant case studies and panel discussion will be used to illustrate current treatment recommendations and highlight newer therapeutic approaches as well as promote interaction and discussion about clinical issues that are still a matter of controversy.

This satellite symposium is directed toward medical oncologists, surgeons, and radiation oncologists interested in the treatment of breast cancer. Physician assistants, research nurses, and fellows interested in the treatment of patients with breast cancer are also invited to attend.

At the conclusion of this symposium, you should be able to:

  • Evaluate the use of biologic agents, including after progression on prior ErbB2-targeted therapy and as frontline therapy, in patients with advanced/metastatic ErbB2+ breast cancer
  • Discuss the biologic rationale for and clinical efficacy and safety of combining ErbB-targeted agents with hormonal or antiangiogenic therapies for the treatment of metastatic breast cancer
  • Incorporate data from clinical trials and current treatment recommendations concerning the combination of targeted therapies for patients with metastatic breast cancer into practice in order to improve treatment decision making

Educational Grants

An educational grant for this activity was provided by:


  1. GlaxoSmithKline