Interview Details - Overview
Expert Interviews in Head and Neck Cancers
Release Date: January 29, 2010|
Expiration Date: January 29, 2011
1.25 AMA PRA Category 1 Credit(s)™|
Jan 29, 2010, Expert Interviews
Learning Objectives
Upon completion of this educational activity, you should be able to:
- Discuss novel agents and efforts to identify predictive biomarkers in SCCHN
- Evaluate the impact of HPV infection on the pathogenesis and progression of oropharyngeal head and neck cancers
- Outline the selection of patients for induction chemotherapy in locally advanced SCCHN
- Assess the efficacy of chemoradiation therapy with or without targeted agents in locally advanced SCCHN
Overview and Purpose
Targeted agents are changing the therapeutic landscape for squamous cell carcinoma of the head and neck (SCCHN). Inhibitors of the epidermal growth factor receptor (EGFR) and angiogenic pathways are being investigated, and antibodies to EGFR are approved for use with radiation therapy as treatment for locally advanced disease and as single-agent therapy in recurrent/metastatic disease. Research to identify predictive biomarkers for therapy is under way, and clinical trials are studying induction therapy and the combination of targeted agents with chemoradiation therapy in patients with locally advanced disease. Differential outcomes that correlate with the presence of the human papillomavirus (HPV) have led to the emergence of a distinct biological subset of SCCHN.
The purpose of this activity is to update physicians on SCCHN biology and the optimization of therapy through the use of biomarkers, induction therapy, and the addition of targeted agents to chemoradiation therapy.
Target Audience
This educational activity is intended for medical oncologists involved in the care of patients with locally advanced SCCHN. No specific skills or knowledge other than a basic training in oncology is required for successful participation in this activity.
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To claim credit for this activity you must:
- Take the Pretest
- Participate in the Activity
- Take the Posttest
- Take the Evaluation
- Claim your Credit Amount & Certificate Type
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